Below are 10 examples of some of his most well-known surviving works. Some of his pieces were completed by assistants, but others were lost, destroyed, or overpainted. Most scholars agree that Leonardo used a bovine heart for all his drawings from around 1513, for which he may have had two reasons. London's Victoria and Albert museum will be hosting an exhibition of Leonardo's work in art, science and technology starting 14 September 2006 to 7 January 2007, in collaboration with Universal Leonardo, Central Saint Martins College of Art and Design, University of the Arts, London. At his death in 1519, Leonardo left many notebooks filled with jottings and sketches but very few finished works. Mr Wells and Leonardo feature in The Secret of Drawing which begins on BBC Two on October 8. Mr Wells is now looking back at many of Leonardo's other drawings of the body to see if these might help medicine now. The Italian artist had no formal medical training and brought together a number of disciplines, including mechanics and engineering, when he looked at a problem. He said Leonardo had a depth of appreciation of the anatomy and physiology of the body - its structure and function - that perhaps has been overlooked by some. Mr Wells says he can now repair the floppy mitral valve in such a way that it does not alter the normal diameter of the valve when it is open which means that the individual can return to more vigorous exercise without any problems. reproduction Article References One of the most important and influential figures of the Renaissance was the painter, sculptor, architect and engineer, Leonardo Da Vinci a man that epitomized the Renaissance humanist ideal. One from the right and one from the posterior side. Leonardo worked out in the 1500s that the opening phase of the mitral valve was extremely important - this can be compromised with conventional surgery because the opening is made narrower than normal. These drawings done by Leonardo da Vinci are two views of the Human heart. Narrowing the diameter of the valve opening with surgery helps, but Mr Wells, with help from Leonardo, believes he has found a better way. He suggested that arteries fur up over a lifetime, creating a health risk In some people it stops working properly, and becomes like a swing door, letting blood flow backwards through it, which means the heart has to work harder to do its job of getting blood out into the arteries and around the body. It works a bit like a pair of doors, slamming shut to stop blood returning from where it came. The job of the mitral valve, which is made up of two flaps, is to stop blood flowing in the wrong direction in the heart. It means that we can repair this valve in a better way." "What Leonardo was saying about the shape of the valve is important. Mr Wells said: "It's a complete rethink of the way we do the mitral valve operation. However, this can restrict the blood flow further when the individual is exercising and working their heart to the maximum. Until now, surgeons have repaired a floppy valve by narrowing its diameter. The drawings allowed him to work out how to restore normal opening and closing function of the mitral valve, one of the four valves in the heart.
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